In 2017, Jennifer Roderer made her house debut at the Metropolitan Opera in Alfano's Cyrano de Bergerac.  In 2015, she created the role of Shifrah Puah in Ben Moore and Nahma Sandrow's new opera Enemies, A Love Story for Palm Beach Opera and joined the roster of the Met where she covered  in  Lulu and later in Jenufa.  

She recently made debuts with  Spoleto Opera  as Kabanicha in Kat'a Kabanova,  Chautauqua Opera debut as Quickly in Falstaff, a role she has also performed with Opera Roanoke and Crested Butte Music Festival, Syracuse Opera  as  Marcellina in Le Nozze di Figaro and  Mrs. Lovett in Sweeney Todd, and reprised  Amneris  in Aida with New Jersey Festival Orchestra.   Other performances include Azucena in Il Trovatore for Opera Roanoke, and  the Witch in Hansel & Gretel  with Utah Opera, a signature role she has also performed with Opera Company of Philadelphia, New York City Opera, Phoenix Symphony, Tulsa Opera and Opera Roanoke, among others. 

With City Opera she has performed a diverse array of operas  including Patience, Plateé,  Dead Man Walking, Lysistrata, and Little Women.  In 2005, she  made a critically acclaimed debut at the Teatro Colòn in Buenos Aires as Fricka in Die Walküre, conducted by Charles Dutoit. Other Wagnerian credits include Die Walküre for Lyric Opera of Chicago, Opera Pacific and Seattle Opera, a Flowermaiden in Parsifal with the Los Angeles Philharmonic conducted by Pierre Boulez, as well as several orchestral concerts with the Wagner Society of Washington D.C. in excerpts from Lohengrin (Ortrud), Götterdämmerung (Waltraute), and Siegfried (Erda). Oft-repeated roles include Mrs. Grose in Turn of the Screw (Toledo Opera, Lyric Opera of Kansas City and Lorin Maazel’s Chateauville Foundation) and Ruth in The Pirates of Penzance (Lyric Opera of Kansas City, Indianapolis Opera and Opera a la Carte).